I thought I would ask here as you're more likely to know than me

I'm shortly going to be completely updating my PC with a midrange scope card at it's hub. Could I have opinions on setups that wouldn't have any compatability issues?
I've no problem buying individual parts
I'm not looking for things like monitors / keyboards, only internal hardware
I guess I'm looking at £400 or so to spend, but there may be a git of give in that amount...
Thank you!
J