PCI era cards are entering the window where heating/cooling cycles will affect solder and Surface mount components, while cards that are left off for long periods of time are in danger of drying out caps.
"I’ve come to the conclusion that synths are like potatoes, they’re no good raw—you’ve got to cook ‘em, and I cooked these sounds for months before I got them to the point where they sounded musical to me." Lyle Mays